Advanced Clinical Stage at Diagnosis of Breast Cancer Is Associated with Poorer Health-Related Quality of Life: A Cross-Sectional Study

Eur J Breast Health 2019;15(1):26-31

DOI: 10.5152/ejbh.2018.4297

1. Department of Clinical Epidemiology, National Cancer Institute, Rio de Janeiro, Brazil

2. CEUMA University, Maranhão, Brazil

3. Federal University of Maranhão, Maranhão, Brazil

4. Estácio College of Amazonas, Manaus, Brazil

No information available.

No information available

Received Date: 07.08.2018

Accepted Date: 12.10.2018

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ABSTRACT

Objective:

To describe the clinical stage in women diagnosed with breast cancer and the association between clinical stage and Health-related quality of life (HRQoL).

Materials and Methods:

This was a cross-sectional study involving women diagnosed with breast cancer. HRQoL was assessed with European Organization for Research and Treatment of Cancer 30-Item Quality of Life Questionnaire and the Quality of Life Questionnaire Breast Cancer 23. The principal exposure was clinical stage (

Results:

In total, 302 women were included. The majority (58.9%) had been diagnosed with advanced stage cancer (≥IIB). Those at an advanced clinical stage had poorer role functioning (p=0.029), pain (p<0.001), and symptoms in the breast (p<0.001).

Conclusion:

Advanced clinical stage at diagnosis was found to be associated with worse health-related quality of life in breast cancer patients.