ABSTRACT

The mesenchymal tumors of the breast are rare and they generally consist less than 1% of all breast tumors. Wide surgical excision with clear surgical margins is the most eff ective treatment. Adjuvant radiotherapy and chemotherapy may be considered in selected patients.

A fourteen year old girl admitted to our breast clinic with a recurrent big mass in her right breast. She underwent an excisional biopsy two times before in diff erent hospitals. And, histopathologic studies showed indiff erentiated sarcoma of the breast without surgical margin examination. At physical examination, she had a 13 cm in diameter mass lesion in her right breast, invading to whole breast, pectoralis major muscle and palpable lymph nodes at ipsilateral axillary region. Right radical mastectomy was performed with reconstruction of chest wall with free skin graft. Pathologic studies were same as previous results of undiff erentiated sarcoma. Following the initial surgical procedure she had 3 cycles vincristine, adriamycine, cyclophosphamide and 3 cycles iphosphomide and etoposide and radiotherapy [total 5040 cGy (thoracic and internal mammarian) irradiation]. She had pulmonary metastases at 12th month and died at 14th month due to systemic metastases to the lungs and the liver.

With this case presentation, we want to remind the possibility of mesenchymal malignant tumors in especially young females. These lesions should be resected with negative surgical margins.