ABSTRACT

Introduction:

Male breast cancer constitutes less than 1% of all cases of breast cancer. In this study, we analyzed clinical and pathological features of male breast cancer cases, which had been followed up and treated at our institution.

Material and Method:

The data regarding the main clinicopathological features of the male breast cancer patients were retrieved from the patients’ records retrospectively.

Results:

A total of 16 patients were included in the analysis with a median age of 60 (41-75). The most common cell type was infiltrating ductal carcinoma, comprising 81.3 % of all cases. Most patients were staged as locally advanced (50% – stage 3) at the time of diagnosis. Estrogen and/or progesterone receptor positivity were found in 13 patients (81.3%). HER2 status could be examined in 9 patients, and 4 patients (25%) found to be positive for HER2 overexpression. Overall survival was 3(1-12) years and disease-free survival was 2 (1-8) years.

Discussion:

Despite the increasing knowledge about breast cancer in women, little is known in case of male breast cancer management. Therefore, there is a strong need to perform randomized studies for the treatment of male breast cancer.