Breast Cancer in Turkey; An Analysis of 20.000 Patients with Breast Cancer
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Original Article
P: 141-146
July 2019

Breast Cancer in Turkey; An Analysis of 20.000 Patients with Breast Cancer

Eur J Breast Health 2019;15(3):141-146
1. Department of Surgery, İstanbul University İstanbul School of Medicine, İstanbul, Turkey
2. Department of Surgery, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Florida, USA
3. Department of Surgery, Akdeniz University School of Medicine, Antalya, Turkey
No information available.
No information available
Received Date: 14.03.2019
Accepted Date: 08.05.2019
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ABSTRACT

Objective:

Breast cancer is the most common type of cancer and the leading cause of cancer-related deaths in women in Turkey. This study presents the characteristics of patients registered in National Breast Cancer Registry Program of Turkish Federation of Breast Diseases Societies.

Materials and Methods:

The registry contains 242 variables under 10 categories and 699 questions. Patients were recorded (online and offline) from nationwide breast centers around Turkey.

Results:

Twenty-thousand patients were registered between May 2005 and April 2017 at 36 centers. After data cleaning, 19,503 women were included in the study. The median age at diagnosis was 51 [14-97]; 17.2% were younger than 40 and 37.2% were premenopausal; 13.6% were nulliparous. Breast conserving surgery rate was 39.3%. Histopathology was invasive ductal cancer in 77%. Majority of patients had stage II cancer (48.3%). Estrogen, progesterone and HER-2 receptor positivity rates in invasive breast cancer were 72.5%, 62.5% and 21.8%, respectively. The mean tumor diameter was 2.5±1.7 cm. During the mean 51.6 months of follow-up, the local/regional and systemic recurrence rates were 3.7% and 5.2%, respectively; five and 10-year overall survival rates were 86% and 76%.

Conclusion:

Despite increasing number of screening centers and free-of-charge mammography (ages 40 to 69) and mobile screening systems in recent years, a significant portion of patients were diagnosed at advanced stage due to lack of breast cancer awareness. In contrast with the study published 5 years ago, there was a decrease in the rate of pre-menopausal women and an increase in the breast conserving surgery.

Keywords:
Breast cancer, demography, reproductive functions, pathology, survival, Turkey