Breast carcinoma is a rare disease in males compared to females and papillary carcinoma of the breast is seen less than 1% of all male breast carcinomas. Solid papillary carcinoma of the breast, with transitional cell epithelium and neuroendocrine differentiation, is a rare entity. We report a 28-year-old male patient with a painless mass in the left breast due to solid papillary carcinoma while receiving anti-tuberculosis therapy. Tumor is characterized by neuroendocrine differentiation with accompanying transitional cell variant epithelium. The tumor was successfully excised. Although solid papillary carcinoma is thought to have a better prognosis than other breast carcinomas, in our patient, local and axillary recurrences were seen in one year, in contrast to reports in the literature. Inconclusion, the solid papillary carcinoma with transitional cell epithelium and neuroendocrine differentiation of breast in a male is a very rare disease. Its prognosis could be worse than reported in the literature.
Keywords: solid papillary carcinoma, neuroendocrine differentiation, transitional epithelium, breast neoplasm, male